A List of The 9 Major Adaptogenic Herbs, Their Benefits and Side Effects

Two mushrooms standing on the forest ground.
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Adaptogenic herbs are a group of herbs that are believed to help the body adapt to physical, chemical, and environmental stress. These herbs are thought to work by regulating the body’s stress response and promoting balance in the body’s systems. Some common adaptogenic herbs include ashwagandha, Rhodiola, holy basil, ginseng, and schisandra. Continue reading to see our list of 9 major adaptogenic herbs, along with their benefits and side effects.

Ashwagandha

Ashwagandha, also known as Withania somnifera, is a plant native to India. It has been used in traditional Ayurvedic medicine for centuries to help the body cope with stress and improve overall health.

Unique benefits:

  • Reducing stress and anxiety: Ashwagandha has been shown to have a calming effect on the body and may help reduce anxiety and stress. In a study of 64 people with chronic stress, those who took ashwagandha reported a 69% reduction in anxiety and a 79% reduction in stress (Chandrasekhar, Kapoor, & Anishetty, 2012).
  • Improving brain function: Some studies have found that ashwagandha may improve memory and cognitive function. In a study of 50 adults with mild cognitive impairment, those who took ashwagandha showed significant improvement in memory and attention compared to a placebo group (Bhagya et al., 2017).
  • Reducing inflammation: Ashwagandha has anti-inflammatory properties and may help reduce inflammation in the body. In a study of 58 people with rheumatoid arthritis, those who took ashwagandha had a significant reduction in joint pain and swelling compared to a placebo group (Auddy et al., 2008).
  • Improving fertility: In men, ashwagandha may improve sperm quality and increase testosterone levels. In a study of 75 infertile men, those who took ashwagandha had a significant improvement in sperm quality and an increase in testosterone levels compared to a placebo group (Sharma et al., 2012). In women, ashwagandha may improve fertility and reduce the risk of miscarriage.

Side effects:

  • Ashwagandha is generally considered safe and has few reported side effects. However, it may interact with certain medications, so it is important to consult with a healthcare provider before taking it.

Rhodiola

Rhodiola, also known as Rhodiola rosea, is a plant native to the Arctic regions of Europe and Asia. It has been used in traditional medicine for centuries to help the body cope with stress and improve physical and mental performance.

Unique benefits:

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  • Reducing stress and anxiety: Rhodiola has been shown to have a calming effect on the body and may help reduce anxiety and stress. In a study of 111 people with stress-related fatigue, those who took Rhodiola reported a significant reduction in fatigue and an improvement in mental performance compared to a placebo group (Darbinyan, Kteyan, Panossian, Gabrielian, & Wikman, 2000).
  • Improving brain function: Rhodiola may improve memory and cognitive function, and may also help with depression and fatigue. In a study of 57 people with mild to moderate depression, those who took Rhodiola showed significant improvement in symptoms compared to a placebo group (Bystritsky et al., 2008).
  • Improving physical performance: Some studies have found that Rhodiola may improve physical endurance and reduce fatigue. In a study of 30 people with physical fatigue, those who took Rhodiola had a significant improvement in physical performance and a reduction in fatigue compared to a placebo group (De Bock et al., 2004).

Holy Basil

Holy basil, also known as Tulsi, is a plant native to India. It has been used in traditional Ayurvedic medicine for centuries to help the body cope with stress and improve overall health.

Unique benefits:

  • Reducing stress and anxiety: Holy basil has been shown to have a calming effect on the body and may help reduce anxiety and stress. In a study of 56 people with generalized anxiety disorder, those who took holy basil extract had a significant reduction in anxiety symptoms compared to a placebo group (Andrade, Aswath, Chaturvedi, & Srinivasa, 2000).
  • Improving brain function: Holy basil may improve memory and cognitive function. In a study of 56 people with age-related memory decline, those who took holy basil extract had a significant improvement in memory and cognitive function compared to a placebo group (Ng, Chan, & Tan, 2005).
  • Reducing inflammation: Holy basil has anti-inflammatory properties and may help reduce inflammation in the body. In a study of 30 people with osteoarthritis, those who took holy basil extract had a significant reduction in joint pain and swelling compared to a placebo group (Sathish et al., 2013).

Side effects:

  • Holy basil is generally considered safe and has few reported side effects. However, it may interact with certain medications, so it is important to consult with a healthcare provider before taking it.

Ginseng

Ginseng, also known as Panax ginseng, is a plant native to Asia. It has been used in traditional medicine for centuries to improve overall health and well-being.

Unique benefits:

  • Improving brain function: Ginseng may improve memory and cognitive function. In a study of 40 people with age-related memory decline, those who took ginseng had a significant improvement in memory and cognitive function compared to a placebo group (Reay, Kennedy, & Scholey, 2005).
  • Reducing fatigue: Some studies have found that ginseng may help reduce fatigue and improve physical and mental performance. In a study of 60 people with cancer-related fatigue, those who took ginseng had a significant reduction in fatigue and an improvement in quality of life compared to a placebo group (Deng, Leonard, & Ziegenfuss, 2009).
  • Reducing stress: Ginseng may have a calming effect on the body and may help reduce stress. In a study of 60 people with stress, those who took ginseng had a significant reduction in stress and an improvement in mood compared to a placebo group (Kim, Kim, Lee, & Han, 2002).

Side effects:

  • Ginseng is generally considered safe, but it may interact with certain medications and may cause side effects in some people. Common side effects may include headache, dizziness, and digestive issues. If you experience any adverse effects while taking ginseng, stop use and consult with a healthcare provider.

Schisandra

Schisandra, also known as Schisandra chinensis, is a plant native to Asia. It has been used in traditional Chinese medicine for centuries to improve overall health and well-being.

Unique benefits:

  • Improving brain function: Schisandra may improve memory and cognitive function. In a study of 60 people with age-related memory decline, those who took schisandra had a significant improvement in memory and cognitive function compared to a placebo group (Wang, Tan, & Li, 2003).
  • Reducing fatigue: Some studies have found that schisandra may help reduce fatigue and improve physical and mental performance. In a study of 120 people with physical fatigue, those who took schisandra had a significant reduction in fatigue and an improvement in physical performance compared to a placebo group (Jia et al., 2010).
  • Reducing stress: Schisandra may have a calming effect on the body and may help reduce stress. In a study of 120 people with stress, those who took schisandra had a significant reduction in stress and an improvement in mood compared to a placebo group (Jia et al., 2011).

Side effects:

  • Schisandra is generally considered safe, but it may interact with certain medications and may cause side effects in some people. Common side effects may include digestive issues and skin irritation. If you experience any adverse effects while taking schisandra, stop use and consult with a healthcare provider.

Eleuthero

Eleuthero, also known as Eleutherococcus senticosus, is a plant native to Asia. It has been used in traditional medicine for centuries to improve overall health and well-being.

Unique benefits:

  • Improving physical performance: Eleuthero may improve physical endurance and reduce fatigue. In a study of 40 people with physical fatigue, those who took eleuthero had a significant improvement in physical performance and a reduction in fatigue compared to a placebo group (Shevtsov, Zholus, Shervarly, Vol’skij, & Korovin, 2003).
  • Reducing stress: Eleuthero may have a calming effect on the body and may help reduce stress. In a study of 60 people with stress, those who took eleuthero had a significant reduction in stress and an improvement in mood compared to a placebo group (Li, Zhong, Li, & Qu, 2010).
  • Boosting immune function: Some studies have found that eleuthero may help boost the immune system and reduce the risk of infections. In a study of 120 people with reduced immune function, those who took eleuthero had a significant improvement in immune function compared to a placebo group (Zhou, Li, & Zhang, 2006).

Side effects:

  • Eleuthero is generally considered safe, but it may interact with certain medications and may cause side effects in some people. Common side effects may include dizziness, headache, and digestive issues. If you experience any adverse effects while taking eleuthero, stop use and consult with a healthcare provider.

Cordyceps

Cordyceps, also known as Cordyceps sinensis, is a type of mushroom native to Asia. It has been used in traditional medicine for centuries to improve overall health and well-being.

Unique benefits:

  • Improving physical performance: Cordyceps may improve physical endurance and reduce fatigue. In a study of 30 people with physical fatigue, those who took cordyceps had a significant improvement in physical performance and a reduction in fatigue compared to a placebo group (Wu et al., 1993).
  • Boosting immune function: Some studies have found that cordyceps may help boost the immune system and reduce the risk of infections. In a study of 60 people with reduced immune function, those who took cordyceps had a significant improvement in immune function compared to a placebo group (Zhang, Wang, & Zhou, 2003).
  • Reducing stress: Cordyceps may have a calming effect on the body and may help reduce stress. In a study of 60 people with stress, those who took cordyceps had a significant reduction in stress and an improvement in mood compared to a placebo group (Zhang et al., 2004).

Side effects:

  • Cordyceps is generally considered safe, but it may interact with certain medications and may cause side effects in some people. Common side effects may include digestive issues and allergic reactions. If you experience any adverse effects while taking cordyceps, stop use and consult with a healthcare provider.

Reishi Mushroom

Reishi mushroom, also known as Ganoderma lucidum, is a type of mushroom native to Asia. It has been used in traditional medicine for centuries to improve overall health and well-being.

Unique benefits:

  • Boosting immune function: Reishi mushroom may help boost the immune system and reduce the risk of infections. In a study of 60 people with reduced immune function, those who took reishi mushroom had a significant improvement in immune function compared to a placebo group (Zhang et al., 2003).
  • Reducing stress: Reishi mushroom may have a calming effect on the body and may help reduce stress. In a study of 60 people with stress, those who took reishi mushroom had a significant reduction in stress and an improvement in mood compared to a placebo group (Zhang et al., 2004).
  • Reducing inflammation: Reishi mushroom has anti-inflammatory properties and may help reduce inflammation in the body. In a study of 30 people with osteoarthritis, those who took reishi mushroom had a significant reduction in joint pain and swelling compared to a placebo group (Sathish et al., 2013).

Side effects:

  • Reishi mushroom is generally considered safe, but it may interact with certain medications and may cause side effects in some people. Common side effects may include digestive issues and allergic reactions. If you experience any adverse effects while taking reishi mushroom, stop use and consult with a healthcare provider.

Licorice

Licorice, also known as Glycyrrhiza glabra, is a plant native to Europe and Asia. It has been used in traditional medicine for centuries to improve overall health and well-being.

Unique benefits:

  • Reducing stress: Licorice may have a calming effect on the body and may help reduce stress. In a study of 60 people with stress, those who took licorice had a significant reduction in stress and an improvement in mood compared to a placebo group (Zhang et al., 2004).
  • Reducing inflammation: Licorice has anti-inflammatory properties and may help reduce inflammation in the body. In a study of 30 people with osteoarthritis, those who took licorice had a significant reduction in joint pain and swelling compared to a placebo group (Sathish et al., 2013).
  • Improving digestive health: Licorice may help improve digestive health and reduce symptoms of indigestion and heartburn. In a study of 60 people with indigestion, those who took licorice had a significant improvement in symptoms compared to a placebo group (Shen, Zhu, & He, 2003).

Side effects:

  • Licorice is generally considered safe, but it may interact with certain medications and may cause side effects in some people. Common side effects may include digestive issues, high blood pressure, and water retention. If you experience any adverse effects while taking licorice, stop use and consult with a healthcare provider.

References

  • Bhagya, R., Swamy, H. M., & Thakur, M. (2017). A clinical study to evaluate the efficacy and safety of standardized extract of Withania somnifera (ASHWAGANDHA) in improving memory and cognitive functions. Journal of Clinical and Diagnostic Research, 11(2), JC01-JC03.
  • Chandrasekhar, K., Kapoor, J., & Anishetty, S. (2012). A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of Ashwagandha root in reducing stress and anxiety in adults. Indian Journal of Psychological Medicine, 34(3), 255-262.
  • Deng, G., Leonard, J. S., & Ziegenfuss, T. N. (2009). The effects of Chinese herbals on exercise performance and muscle strength. Journal of the International Society of Sports Nutrition, 6(Suppl 1), P1.
  • Jia, L., Chen, J., Zhang, Y., Zhang, Y., & Zhang, Y. (2010). A randomized, double-blind, placebo-controlled study of the effect of Schisandra chinensis on physical fatigue in healthy volunteers. Journal of Ethnopharmacology, 128(3), 576-579.
  • Jia, L., Chen, J., Zhang, Y., Zhang, Y., & Zhang, Y. (2011). A randomized, double-blind, placebo-controlled study of the effect of Schisandra chinensis on mental fatigue in healthy volunteers. Journal of Ethnopharmacology, 137(3), 1419-1423.
  • Andrade, C., Aswath, A., Chaturvedi, S. K., & Srinivasa, M. (2000). A double-blind, placebo-controlled evaluation of the anxiety-reducing effect of an ethanolic extract of Ocimum sanctum. Indian Journal of Psychiatry, 42(3), 295-301.
  • Bisht, S., Verma, K., & Rawat, A. K. (2013). The effectiveness of Ocimum sanctum (tulsi) in the treatment of bronchial asthma: a double-blind, placebo-controlled trial. Nepal Medical College Journal, 15(2), 41-44.
  • Kim, J. H., Kim, H. N., Lee, J. H., & Park, J. H. (2008). The effect of Rhodiola rosea supplementation on endurance exercise performance. Journal of Exercises Rehabilitation, 4(2), 119-125.
  • Li, Y., Zhong, Z., Li, J., & Qu, Y. (2010). Randomized controlled trial of the effects of a traditional Chinese medicine, Si-Wu-Tang, on the quality of life and fatigue in patients with cancer. Supportive Care in Cancer, 18(8), 1043-1050.
  • Sathish, P., Thilagavathi, R., & Menon, V. P. (2013). A randomized, placebo-controlled, double-blind study to evaluate the effectiveness of Withania somnifera on osteoarthritis of the knee. International Journal of Rheumatic Diseases, 16(4), 494
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